Makes you forget about Xanax

Alprazolam AbZ 0.25 mg tablets

AbZ-Pharma GmbH - Business address -

Active ingredientAddictive drugPsychotropic
Pharmacological groupAnxiolytics

All information


AbZ-Pharma GmbH - Business address -

What is it and what is it used for?

Alprazolam AbZ 0.25 mg belongs to the group of benzodiazepines. These influence messenger substances in the brain and help treat anxiety.

Alprazolam AbZ 0.25 mg is used

- for the symptomatic treatment of anxiety


What do you need to consider before use?

Alprazolam AbZ 0.25 mg must not be taken

  • if you are allergic to alprazolam, other benzodiazepines or any of the other ingredients of this medicine (listed in section 6).
  • if you have a specific type of severe muscle weakness (myasthenia gravis).
  • if you have severe breathing problems.
  • if you sometimes stop breathing at night (sleep apnea syndrome).
  • if you have severe liver problems.
  • in the event of acute poisoning with alcohol or other substances that affect the brain.
Warnings and Precautions

Talk to your doctor or pharmacist before taking Alprazolam AbZ 0.25 mg.

  • if you have a history of addiction (alcohol, drug, drug abuse)
  • if you have difficulty breathing or breathing problems
  • if you have impaired kidney function or mild to moderate liver problems
Talk into these Check with your doctor, the dose may need to be reduced.

Alprazolam AbZ 0.25 mg should only be used if your anxiety states severely interfere with your daily life.

Benzodiazepines, as well as Alprazolam AbZ 0.25 mg, should not be taken for the sole treatment of depression or other disorders of the mental and emotional state. Under certain circumstances, the depressive symptoms can be exacerbated if the underlying disease is not adequately treated. If you have ever felt so useless or worthless that you thought about killing yourself, it is very important that you speak to your doctor or family about it as they can help you.

The duration of treatment should be as short as possible and not exceed 8-12 weeks (see section 3 under "How should Alprazolam AbZ 0.25 mg?").

If you take Alprazolam AbZ 0.25 mg continuously for a few weeks, the effect may decrease.

Long-term use of Alprazolam AbZ 0.25 mg can lead to physical and psychological dependence. The risk of addiction increases with the dosage level and the length of treatment. This is especially true for patients with a history of drug, drug and alcohol abuse. If physical addiction has developed, withdrawal symptoms such as headache, muscle pain, severe anxiety and tension, sleep disorders, restlessness, confusion and irritability will develop on discontinuation of treatment. In serious In all cases, the following symptoms can occur: depersonalization and derealization (impaired perception of oneself or the environment), increased hearing, abnormal sensations such as numbness and tingling of the limbs, sensitivity to light, noise and touch, hallucinations and epileptic seizures. Withdrawal symptoms can occur several days after the end of therapy.

When treatment with Alprazolam AbZ 0.25 mg is stopped, the symptoms that originally caused the treatment may reappear in an aggravated form. This can be accompanied by mood swings, anxiety, or insomnia and restlessness.

Since the risk of these side effects occurring after a rapid dose reduction or sudden discontinuation of treatment is greater, the dose should be reduced gradually (tapering off).

Patients with impaired liver function

Talk to your doctor if your liver function is impaired, the dose may have to be reduced (see section 2. under “Alprazolam AbZ 0.25 mg must not be taken”).

Patients with impaired renal function

Talk to your doctor if your kidney function is impaired, the dose may need to be reduced.

Elderly or debilitated people

Benzodiazepines and benzodiazepine-related drugs should be used with caution in the elderly as sedation (calming) and / or muscle weakness can increase the risk of falls. In the elderly, falls often lead to serious consequences. The doctor may prescribe a lower dose for elderly or debilitated people.

Children and adolescents

The use of alprazolam is not recommended in children and adolescents under 18 years of age.

Other medicines and Alprazolam AbZ 0.25 mg

Tell your doctor or pharmacist if you are taking / using, have recently taken / used or may take / use any other medicines.

In particular, ask your doctor for advice if you are already taking any of the following medicines:

  • Medicines to treat fungal infections (e.g. ketoconazole, itraconazole, posaconazole, voriconazole)
  • Sleep pills, antipsychotics, or anesthetics
  • Pain relievers (such as dextropropoxyphene or opioids)
  • Medicines used to treat depression (such as St. John's wort, fluoxetine, fluvoxamine, sertraline, nefazodone, imipramine, and desipramine)
  • Anxiolytics (used to treat anxiety)
  • Medicines used to treat schizophrenia (e.g. clozapine)
  • Medicines to treat epileptic seizure disorders (e.g. carbamazepine, phenytoin)
  • soothing (sedative) antihistamines (drugs against allergies with calming as a side effect)
  • hormone-containing medicines for contraception ("pill")
  • Antibiotics (e.g. erythromycin, troleandomycin, rifampicin, clarithromycin, telithromycin)
  • Medicines used to treat heart problems (e.g. digoxin)
  • medicines to lower blood pressure (e.g. diltiazem)
  • muscle relaxing medicines
  • Medicines used to treat HIV
  • Cimetidine (medicine for excessive stomach acid)
Taking Alprazolam AbZ 0.25 mg together with alcohol

Do not drink alcohol during treatment with Alprazolam AbZ 0.25 mg! Alcohol can change the mode of action of Alprazolam AbZ 0.25 mg and increase the calming effect.

pregnancy and breast feeding period

Ask your doctor or pharmacist for advice before taking this medicine if you are pregnant or breastfeeding, think you may be pregnant or plan to become pregnant.


During pregnancy, Alprazolam AbZ 0.25 mg should only be prescribed in exceptional cases and for compelling reasons. If you want to become pregnant or suspect that you are pregnant during treatment with Alprazolam AbZ, please inform your doctor immediately. He / she can decide whether to continue or discontinue your treatment.


Alprazolam is excreted in breast milk. You should therefore not breast-feed during treatment with Alprazolam AbZ 0.25 mg.

Ability to drive and ability to operate machines

Alprazolam AbZ 0.25 mg can cause side effects such as drowsiness, memory disorders, difficulty concentrating and muscle weakness and thereby your impair the ability to drive and use machines. This effect is intensified by alcohol. If you haven't slept enough, your alertness will decrease even more.

Do not drive or use machines while taking alprazolam.

1-2 tablets of Alprazolam AbZ 0.25 mg 3 times a day (equivalent to 0.25-0.5 mg alprazolam 3 times a day). If necessary, the dose can be increased every 3-4 days to: 2 to a maximum of 12 tablets Alprazolam AbZ 0.25 mg per day, divided into several individual doses (corresponding to 0.5-3 mg alprazolam per day). Alprazolam AbZ 0.25 mg contains lactose

Therefore, please only take Alprazolam AbZ 0.25 mg after consulting your doctor if you know that you suffer from an intolerance to certain sugars.

How is it used?

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

Unless otherwise prescribed by your doctor, the recommended dose is


Initial dosage:

Maintenance dosage:

Elderly patients, weakened patients or patients with kidney or liver dysfunction Initial dose: 1 tablet Alprazolam AbZ 0.25 mg 2-3 times a day (corresponding to 2-3 times

0.25 mg alprazolam daily).

If necessary and if the clinical picture allows, the dose can be increased at intervals of 3-4 days to:

Maintenance dose: a maximum of 6 tablets of Alprazolam AbZ 0.25 mg per day, divided into several individual doses.

A lower dose (3 tablets Alprazolam AbZ 0.25 mg, corresponding to 0.75 mg alprazolam per day) is recommended for frail patients or weakened patients with impaired kidney or liver function.

For doses that cannot be adhered to with Alprazolam AbZ 0.25 mg, tablets with 0.5 mg and 1.0 mg alprazolam are available.

If you experience any side effects, please contact your doctor. The dose may need to be reduced.

If the dose needs to be increased, the dose should first be increased in the evening before increasing the dose during the day.

type of application

Take Alprazolam AbZ 0.25 mg tablets whole with plenty of liquid (e.g. a glass of water). Do not chew the tablets.

Duration of application

The duration of treatment with Alprazolam AbZ 0.25 mg should be as short as possible.

After prolonged use, the treatment should be discontinued gradually (reduction of the daily dose by no more than 0.5 mg every 3 days).

The total duration of treatment, including the gradual withdrawal phase, should not exceed 8-12 weeks; ultimately, the attending physician decides on the duration of use.

Please talk to your doctor or pharmacist if you have the impression that the effect of Alprazolam AbZ 0.25 mg is too strong or too weak.

If you take more Alprazolam AbZ 0.25 mg than you should

In any case, ask a doctor immediately (e.g. emergency room at the nearest hospital, poison control center) for advice!

An overdose generally manifests itself in the form of drowsiness, sometimes up to a coma. In lighter ones In cases of overdose, symptoms such as drowsiness, mental confusion, and lethargy will occur. In more severe forms, disorders of the movement sequences, muscle relaxation, drop in blood pressure and disorders of the respiratory function are observed. Coma rarely occurs; very rarely does death follow.

The doctor should assess the severity of the poisoning and determine the necessary further measures.

If you forget to take Alprazolam AbZ 0.25 mg

Do not take a double dose to make up for a forgotten dose.

If you stop taking Alprazolam AbZ 0.25 mg

After a longer period of use and after suddenly stopping treatment, your original symptoms may temporarily worsen again. This can be accompanied by mood swings, anxiety, insomnia, and restlessness.

Therefore the dose should be gradually reduced by the attending physician when the treatment is stopped.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

What are the possible side effects?

Like all medicines, this medicine can have side effects, although not everybody gets them.

Drowsiness, emotional dullness, decreased alertness, confusion, fatigue, headache, dizziness, muscle weakness, movement disorders, visual disturbances (such as double vision or blurred vision) occur predominantly at the beginning of treatment or at higher doses and usually develop in the course of further treatment.

The following side effects are very common (may affect more than 1 in 10 people): sedation, drowsiness

The following side effects are common (affects 1 to 10 users in 100): irritability, confusion, depression, poor appetite, incoordination, uncoordinated movements, impaired memory, sluggish speech, difficulty concentrating, dizziness, constipation, nausea, headache, dizziness, blurred vision, weakness

The following side effects occur uncommonly (affects 1 to 10 users in 1000): muscle weakness, high blood prolactin, hallucinations, tantrums, aggressive behavior, hostile behavior, anxiety, restlessness, changes in sexual desire, insomnia, abnormal thinking, nervousness, stimulation, involuntary movements, tremors, memory loss, vomiting, abnormal liver function, jaundice (yellowing of the skin), dermatitis, incontinence, urination problems, sexual dysfunction, irregular periods, weight change, increase in intraocular pressure

Other side effects that may occur (frequency not known):

Hepatitis, swelling (mainly in the legs and emotional dullness, decreased alertness, fatigue, double vision, diarrhea, increased appetite, difficulty swallowing, low blood pressure, skin reactions, dry mouth, increased salivation, nasal congestion, palpitations, swelling (mainly of the eyelids, face, lips, tongue and throat), which can cause breathing problems


Alprazolam can cause temporary memory lapses (anterograde amnesia). This means that (in most In some cases, a few hours after taking the medication, actions may be carried out that the patient will not be able to remember later. This risk depends on the level of the dosage.


In some In all cases, manic episodes have been reported in patients with latent depression (i.e., symptom-free, pre-existing depression).

Psychiatric and “paradoxical” reactions

When using Alprazolam AbZ 0.25 mg, especially in older patients, hallucinations and so-called "paradoxical reactions" such as restlessness, irritability, aggressive behavior, nightmares, hallucinations, delusions, inappropriate behavior and other behavioral disorders can occur. In such In any case, the doctor should stop treatment with this preparation.


Physical and psychological dependence may develop with the use of alprazolam and its effectiveness may decrease after repeated use for a few weeks. When treatment is discontinued, withdrawal symptoms such as headache, muscle pain, severe anxiety and tension, sleep disorders, restlessness, confusion and irritability may occur. In serious In all cases, the following complaints can occur: depersonalization and derealization (impaired perception of oneself or the environment), increased hearing, abnormal sensations such as numbness and tingling of the limbs, sensitivity to light, noise and touch, hallucinations and epileptic seizures. The original clinical picture can temporarily reappear more intensely.

Cases of abuse have been described.

Reporting of side effects

If you get any side effects, talk to your doctor or pharmacist. This also applies to side effects not listed in this leaflet. You can also report side effects directly to the Federal Institute for Drugs and Medical Devices, Dept. Pharmacovigilance, Kurt-Georg-Kiesinger-Allee 3, D-53175 Bonn, website: By reporting side effects you can help provide more information on the safety of this medicine.

How should it be stored?

Keep this medicine out of the sight and reach of children.

Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of the month indicated.

Do not store above 25 ° C.

Store in the original package in order to protect from light and moisture.

Do not dispose drugs in the wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. You help to protect our environment.

additional Information

What Alprazolam AbZ 0.25 mg contains

The active ingredient is alprazolam.

Each tablet contains 0.25 mg alprazolam.

The other ingredients are:

Docusate sodium, sodium benzoate, pregelatinized starch, microcrystalline cellulose, lactose monohydrate, magnesium stearate (Ph. Eur.), Highly dispersed silicon dioxide.

What Alprazolam AbZ 0.25 mg looks like and contents of the pack

Elongated, scored white tablets.

Alprazolam AbZ 0.25 mg is available in packs of 10, 20 and 50 tablets. Not all pack sizes may be marketed.

Pharmaceutic entrepreneur

AbZ-Pharma GmbH

Graf-Arco-Str. 3

89079 Ulm


Merckle GmbH

Ludwig-Merckle-Str. 3

89143 Blaubeuren

This medicinal product is approved in the member states of the European Economic Area (EEA) under the following names:

GermanyAlprazolam AbZ 0.25 mg tablets
NetherlandsAlprazolam-ratiopharm 0.25 mg, tablets
PortugalAlprazolam ratiopharm 0.25 mg Comprimidos
This leaflet was last revised in December 2015

AbZ-Pharma wishes you a speedy recovery!

Version code: Z09

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